Professor Adam G. Dunn

Professor of Biomedical Informatics
The University of Sydney

Vested interests in healthcare, as usual

Amy Wang and colleagues from Mayo Clinic write about the tendancy for authors with financial ties to GlaxoSmithKline to write favourably about the drug Rosiglitazone, which has been linked to increased risk of myocardial function and is arguably less useful than another drug on the market, Pioglitazone. Both drugs are used in diabetes care.

Fiona Godlee yesterday likened the problem to that of a similar case featuring calcium channel blockers back in 1998. The situation has improved slightly since then, but I personally believe that you can’t stop people from NOT publishing negative results if they have vested interests, you can only encourage and support researchers without vested interests to do objective reviews. If people are unwilling to shoot themselves in the foot, then what place is there for research that comes from those who are essentially attempting to market their work in a scientific manner. Policing comes from review and journal acceptance rates, not from forcing people to reveal data.

Vested interests in healthcare, as usual

  • On the value of deplatforming, and seeing online misinformation as an opportunity to counter misinformed beliefs in front of a key audience
  • Do Twitter bots spread vaccine misinformation?
  • trial2rev: seeing the forest for the trees in the systematic review ecosystem
  • How articles from financially conflicted authors are amplified, why it matters, and how to fix it.
  • Thinking outside the cylinder: on the use of clinical trial registries in evidence synthesis communities
  • Differences in exposure to negative news media are associated with lower levels of HPV vaccine coverage